Four-Octyl itaconate ameliorates periodontal destruction via Nrf2-dependent antioxidant system

• Principais autores: Liangjing Xin (Autor), Fuyuan Zhou (Autor), Chuangwei Zhang (Autor), Wenjie Zhong (Autor), Shihan Xu (Autor), Xuan Jing (Autor), Dong Wang (Autor), Si Wang (Autor), Tao Chen (Autor), Jinlin Song (Autor)
• Formato: Livro
• Publicado em: Nature Publishing Group, 2022-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Periodontitis is a widespread oral disease characterized by continuous inflammation of the periodontal tissue and an irreversible alveolar bone loss, which eventually leads to tooth loss. Four-octyl itaconate (4-OI) is a cell-permeable itaconate derivative and has been recognized as a promi...