MicroRNA-106b Regulates Expression of the Tumour Suppressors p21 and TXNIP and Promotes Tumour Cell Proliferation in Mycosis Fungoides

• Main Authors: Lise M. Lindahl (Author), Maria Gluud (Author), Thomas Emmanuel (Author), Emil A. Thomsen (Author), Tengpeng Hu (Author), Anne H. Rittig (Author), Pamela Celis (Author), Veronica Stolearenco (Author), Thorbjørn Krejsgaard (Author), Claus Johansen (Author), Andreas Willerslev-Olsen (Author), Terkild B. Buus (Author), Anders Woetmann (Author), Lars Aagaard (Author), Carsten Geisler (Author), Thomas Litman (Author), Jacob G. Mikkelsen (Author), Niels Odum (Author), Lars Iversen (Author)
• Format: Book
• Published: Medical Journals Sweden, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A prognostic 3-miRNA classifier for early-stage mycosis fungoides has been developed recently, with miR-106b providing the strongest prognostic power. The aim of this study was to investigate the molecular function of miR-106b in mycosis fungoides disease progression. The cellular localization of mi...