Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects

• Những tác giả chính: Shiwu Zhang (Tác giả), Dan Zhang (Tác giả), Zhengduo Yang (Tác giả), Xipeng Zhang (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2016-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

We previously reported that polyploid giant cancer cells (PGCGs) induced by CoCl2 could form through endoreduplication or cell fusion. A single PGCC formed tumors in immunodeficient mice. PGCCs are also the key contributors to the cellular atypia and associate with the malignant grade of tumors. PGC...