Ultrasound-Mediated Blood-Brain Barrier Disruption for Drug Delivery: A Systematic Review of Protocols, Efficacy, and Safety Outcomes from Preclinical and Clinical Studies

• Autori principali: Kushan Gandhi (Autore), Anita Barzegar-Fallah (Autore), Ashik Banstola (Autore), Shakila B. Rizwan (Autore), John N. J. Reynolds (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Ultrasound-mediated blood-brain barrier (BBB) disruption has garnered focus as a method of delivering normally impenetrable drugs into the brain. Numerous studies have investigated this approach, and a diverse set of ultrasound parameters appear to influence the efficacy and safety of this approach....