Modeling and Simulation to Support Phase Ib/IIa Dose Selection for WBP216, A Long Half-Life Fully Human Monoclonal Antibody Against Interleukin-6

WBP216 is an innovative IL-6 antibody, presenting high affinity to IL-6 and a long half-life (40-60 days). To optimize the dosage regimen for future clinical trials, pharmacokinetics (PK) and pharmacodynamics (PD) of WBP216 would be firstly characterized in Chinese rheumatoid arthritis (RA) patients...

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Bibliographic Details
Main Authors: Xiange Tang (Author), Xiaofeng Zeng (Author), Xiaoduo Guan (Author), Rui Chen (Author), Pei Hu (Author)
Format: Book
Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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