Angiotensin II type 1 receptor autoantibody blockade improves cerebral blood flow autoregulation and hypertension in a preclinical model of preeclampsia

• المؤلفون الرئيسيون: Jeremy W. Duncan (مؤلف), Daniel Azubuike (مؤلف), George W. Booz (مؤلف), Brandon Fisher (مؤلف), Jan M. Williams (مؤلف), Fan Fan (مؤلف), Tarek Ibrahim (مؤلف), Babbette LaMarca (مؤلف), Mark W. Cunningham (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2020-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Introduction:Women with preeclampsia (PE) and reduced uterine perfusion pressure (RUPP) pre-clinical rat model of PE have elevated angiotensin II type 1 receptor agonistic autoantibodies (AT1-AA) and cerebrovascular dysfunction. Methods:Sprague Dawley rats had RUPP surgery with/without AT1-AA inhibi...