Praziquantel-Clays as Accelerated Release Systems to Enhance the Low Solubility of the Drug

• Main Authors: Ana Borrego-Sánchez (Author), Rita Sánchez-Espejo (Author), Fátima García-Villén (Author), César Viseras (Author), C. Ignacio Sainz-Díaz (Author)
• 格式: 圖書
• 出版: MDPI AG, 2020-09-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Praziquantel is an antiparasitic drug indicated for the treatment of the schistosomiasis disease. This drug has very low aqueous solubility, requiring high oral doses for its administration which gives rise to side effects, therapeutic noncompliance and the appearance of resistant forms of the paras...