MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation

• Main Authors: Maria J. Santiago (Author), Srinivasan Chinnapaiyan (Author), Kingshuk Panda (Author), Md. Sohanur Rahman (Author), Suvankar Ghorai (Author), Joseph H. Lucas (Author), Stephen M. Black (Author), Irfan Rahman (Author), Hoshang J. Unwalla (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Transforming Growth Factor Beta1 (TGF-β1) signaling is upregulated in Chronic Obstructive Pulmonary disease (COPD), smokers, and people living with HIV. Cigarette smoking and HIV are also independent risk factors for COPD. Chronic inflammation is a hallmark of COPD. However, the underlying...