Screening for effective cell-penetrating peptides with minimal impact on epithelial cells and gut commensals in vitro

• Huvudupphovsmän: Hitesh P. Gelli (Författare, medförfattare), Ruben Vazquez-Uribe (Författare, medförfattare), Morten Otto Alexander Sommer (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

One of the biggest challenges for oral drug absorption is the epithelial barrier of the gastrointestinal tract. The use of cell-penetrating peptides (CPPs) to modulate the epithelial barrier function is known to be an effective strategy to improve drug absorption and bioavailability. In this study w...