Dissolution enhancement of Gefitinib by solid dispersion and complexation with β-cyclodextrins: In vitro testing, cytotoxic activity, and tablet formulation

Dissolution enhancement of Gefitinib by solid dispersion and complexation with β-cyclodextrins: In vitro testing, cytotoxic activity, and tablet formulation

Cancer is the leading cause of mortality worldwide. In patients with metastatic non-small cell lung cancer, epidermal growth factor receptor (EGFR) is often overexpressed. Gefitinib (GEF), an inhibitor of EGFR, is approved for the treatment of patients with metastatic non-small cell lung cancer (NSC...

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Main Authors: Adel F. Alghaith (Author), Gamal M. Mahrous (Author), Ahmed S. Alenazi (Author), Suliaman M. ALMufarrij (Author), Mohammed S. Alhazzaa (Author), Awwad A. Radwan (Author), Abdullah S. Alhamed (Author), Mohamed S. Bin Salamah (Author), Sultan Alshehri (Author)
Format: Book
Published: Elsevier, 2024-06-01T00:00:00Z.
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