Native size-exclusion chromatography-mass spectrometry: suitability for antibody-drug conjugate drug-to-antibody ratio quantitation across a range of chemotypes and drug-loading levels

Native size-exclusion chromatography-mass spectrometry (nSEC-MS) is an analytical methodology that is appropriate for accurately quantitating the drug-to-antibody ratio (DAR) on a wide variety of interchain cysteine-linked antibody-drug conjugates (ADCs), irrespective of chemotype. In the current pr...

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Bibliographic Details
Main Authors: Jay Jones (Author), Laura Pack (Author), Joshua H. Hunter (Author), John F. Valliere-Douglass (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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