Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis

• Main Authors: Jingjing Wei (Author), Yuan Tian (Author), Meiqi Guan (Author), Jinshu Wei (Author), Yong Ji (Author), Guozhong Tao (Author), Karl G. Sylvester (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives Necrotizing enterocolitis (NEC) is a common and sometimes fatal disease affecting premature infants. Elevated formate has been found in the stool of patients with NEC. Sodium formate (NaF) is used to explore the role of formate in the intestinal epithelial injury.Methods In this study, 15...