Selinexor and Other Selective Inhibitors of Nuclear Export (SINEs)-A Novel Approach to Target Hematologic Malignancies and Solid Tumors
Exportin 1 (XPO1) is a crucial molecule of nucleocytoplasmic transport. Among others, it exports molecules important for oncogenesis from the nucleus to the cytoplasm. The expression of XPO1 is increased in numerous malignancies, which contributes to the abnormal localization of tumor suppressor pro...
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MDPI AG,
2023-05-01T00:00:00Z.
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