Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B

• Main Authors: Rosa Gaglione (Author), Giovanni Smaldone (Author), Angela Cesaro (Author), Mariano Rumolo (Author), Maria De Luca (Author), Rocco Di Girolamo (Author), Luigi Petraccone (Author), Pompea Del Vecchio (Author), Rosario Oliva (Author), Eugenio Notomista (Author), Emilia Pedone (Author), Angela Arciello (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Host defense peptides (HDPs) are gaining increasing interest, since they are endowed with multiple activities, are often effective on multidrug resistant bacteria and do not generally lead to the development of resistance phenotypes. Cryptic HDPs have been recently identified in human apolipoprotein...