Altered intravenous drug disposition in people living with cystic fibrosis: A meta‐analysis integrating top‐down and bottom‐up data

• Main Authors: Pieter‐Jan De Sutter (Author), Maxime Van Haeverbeke (Author), Eva Van Braeckel (Author), Stephanie Van Biervliet (Author), Jan Van Bocxlaer (Author), An Vermeulen (Author), Elke Gasthuys (Author)
• Format: Book
• Published: Wiley, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cystic fibrosis (CF) has been linked to altered drug disposition in various studies. However, the magnitude of these changes, influencing factors, and underlying mechanisms remain a matter of debate. The primary aim of this work was therefore to quantify changes in drug disposition (top‐dow...