Antidepressant effects of total iridoids of Valeriana jatamansi via the intestinal flora-blood-brain barrier pathway

• Main Authors: Li Zhang (Author), Liwen Wang (Author), Li Huang (Author), Yanni Zhao (Author), Hongling Ding (Author), Binglong Li (Author), Lingmiao Wen (Author), Wei Xiong (Author), Yanjun Liu (Author), Tinglan Zhang (Author), Liudai Zhang (Author), Lanlan Wu (Author), Qing Xu (Author), Yuqing Fan (Author), Guihua Wei (Author), Qiaozhi Yin (Author), Yunhui Chen (Author), Tiane Zhang (Author), Zhiyong Yan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Valeriana jatamansi Jones [syn. V. wallichii DC, (Valerianaceae)] (VJJ) is used to treat depression. Objective To explore the effects of total iridoids of VJJ extract (TIV) on chronic unpredictable mild stress (CUMS) in mice. Materials and methods VJJ roots and rhizomes were extracted with 7...