Altered function of arcuate leptin receptor expressing neuropeptide Y neurons depending on energy balance

• Main Authors: Nicola J. Lee (Author), Jennifer Oraha (Author), Yue Qi (Author), Ronaldo F. Enriquez (Author), Ramon Tasan (Author), Herbert Herzog (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: One of leptin's main targets in the hypothalamus are neuropeptide Y (NPY) neurons, with selective deletion of leptin receptors (Lepr) specifically in Npy neurons resulting in major alterations of energy partitioning between fat and bone mass. However, the specific action of these Npy...