220 mutation in the hemagglutinin of avian influenza A (H7N9) virus alters antigenicity during vaccine strain development

• Main Authors: Liqi Liu (Author), Jian Lu (Author), Zi Li (Author), Jianfang Zhou (Author), Junfeng Guo (Author), Xiyan Li (Author), Jia Liu (Author), Yuelong Shu (Author), Dayan Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since the first confirmed case of H7N9 infection was reported in China, there have been five epidemic waves of human H7N9 infections between 2013 and 2017. The fifth wave differed from the previous four waves in that highly pathogenic avian influenza (HPAI) H7N9 viruses with multiple basic amino aci...