Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma

<p>Abstract</p> <p>Background</p> <p>Abberant DNA methylation at CpG dinucleotides represents a common mechanism of transcriptional silencing in cancer. Since CpG methylation is a reversible event, tumor supressor genes that have undergone silencing through this mechani...

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Main Authors: Halaban Ruth (Author), Ma Shuangge (Author), Tran Nam (Author), Rubinstein Jill C (Author), Krauthammer Michael (Author)
Format: Book
Published: BMC, 2010-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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