A tumor microenvironment-responsive micelle co-delivered radiosensitizer Dbait and doxorubicin for the collaborative chemo-radiotherapy of glioblastoma

• Main Authors: Shuyue Zhang (Author), Xiuxiu Jiao (Author), Michal Heger (Author), Shen Gao (Author), Mei He (Author), Nan Xu (Author), Jigang Zhang (Author), Mingjian Zhang (Author), Yuan Yu (Author), Baoyue Ding (Author), Xueying Ding (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma is rather recalcitrant to existing therapies and effective interventions are needed. Here we report a novel microenvironment-responsive micellar system (ch-K5(s-s)R8-An) for the co-delivery of the radiosensitizer Dbait and the chemotherapeutic doxorubicin (DOX) to glioblastoma. Accordin...