Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway

• Main Authors: Yang-Yang Gu (Author), Xiao-Hui Tan (Author), Wen-Peng Song (Author), Wei-Dong Song (Author), Yi-Ming Yuan (Author), Zhong-Cheng Xin (Author), Jia-Dong Wang (Author), Dong Fang (Author), Rui-Li Guan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Endothelial dysfunction is commonly accompanied by a reduced capacity for nitric oxide (NO) production and decreased NO sensitivity, playing a central role in numerous vascular diseases. Saturated free fatty acids are known to reduce NO production and then induce endothelial dysfunction....