Target product profile for a dengue pre-vaccination screening test.

• Main Authors: Noah Fongwen (Author), Annelise Wilder-Smith (Author), Duane J Gubler (Author), Eng Eong Ooi (Author), Edsel Maurice T Salvana (Author), Xavier de Lamballerie (Author), Piero L Olliaro (Author), Rosanna W Peeling (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

With increasing geographic spread, frequency, and magnitude of outbreaks, dengue continues to pose a major public health threat worldwide. Dengvaxia, a dengue live-attenuated tetravalent vaccine, was licensed in 2015, but post hoc analyses of long-term data showed serostatus-dependent vaccine perfor...