Post-Translational Modifications of p53 in Ferroptosis: Novel Pharmacological Targets for Cancer Therapy

• Главные авторы: Le Zhang (Автор), Ningning Hou (Автор), Bing Chen (Автор), Chengxia Kan (Автор), Fang Han (Автор), Jingwen Zhang (Автор), Xiaodong Sun (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Предметы: article
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The tumor suppressor p53 is a well-known cellular guardian of genomic integrity that blocks cell cycle progression or induces apoptosis upon exposure to cellular stresses. However, it is unclear how the remaining activities of p53 are regulated after the abrogation of these routine activities. Ferro...