Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain

• Main Authors: Koichi Kawada (Author), Masayuki Kaneko (Author), Yasuyuki Nomura (Author), Seisuke Mimori (Author), Hiroshi Hamana (Author), Kiyokazu Ogita (Author), Toshihiko Murayama (Author), Hiromichi Fujino (Author), Yasunobu Okuma (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Neural stem/progenitor cells (NSCs) reside in the subventricular zone (SVZ) and subgranular zone of the hippocampal dentate gyrus in adult mammals. The ubiquitin ligase HRD1 is associated with degradation of amyloid precursor protein and believed to be specifically expressed in neurons an...