Achillin Increases Chemosensitivity to Paclitaxel, Overcoming Resistance and Enhancing Apoptosis in Human Hepatocellular Carcinoma Cell Line Resistant to Paclitaxel (Hep3B/PTX)

• Main Authors: Jessica Nayelli Sanchez-Carranza (Author), Leticia González-Maya (Author), Rodrigo Said Razo-Hernández (Author), Enrique Salas-Vidal (Author), Ninfa Yaret Nolasco-Quintana (Author), Aldo F. Clemente-Soto (Author), Lucero García-Arizmendi (Author), Mariana Sánchez-Ramos (Author), Silvia Marquina (Author), Laura Alvarez (Author)
• Format: Book
• Published: MDPI AG, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance (MDR) has become a major obstacle in the treatment of cancer, and is associated with mechanisms such as increased drug outflow, reduction of apoptosis, and/or altered drug metabolism. These problems can be mitigated by the coadministration of agents known as chemosensitizers, as...