Anticancer activity of Aucklandia costus Falc. terpenes: Targeting MDM2 protein inhibition for therapeutic advancements

• Ngā kaituhi matua: Theresia Indah Budhy (Author), Ira Arundina (Author), Anis Irmawati (Author), Sidarningsih (Author), Meircurius Dwi Condro Surboyo (Author), Cecillia Octavianni Raharjo (Author), Ciptantyo Septyan Akbar (Author), Malika Qadira Rahmalia (Author)
• Hōputu: Pukapuka
• I whakaputaina: GarVal Editorial Ltda., 2024-07-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Context: Protein 53 (p53) is a well-known tumor suppressor protein, while murine double minute 2 (MDM2) acts as a negative regulator of p53, leading to p53 inactivation and cancer development. Aucklandia costus Falc. or Saussurea lappa contains bioactive compounds, particularly terpenoids, known for...