Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs

• Prif Awduron: John N. Van den Anker (Awdur), Susan McCune (Awdur), Pieter Annaert (Awdur), Gerri R. Baer (Awdur), Yeruk Mulugeta (Awdur), Ramy Abdelrahman (Awdur), Kunyi Wu (Awdur), Kevin M. Krudys (Awdur), Jeffrey Fisher (Awdur), William Slikker (Awdur), Connie Chen (Awdur), Gilbert J. Burckart (Awdur), Karel Allegaert (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2020-07-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Drug dosing in neonates should be based on integrated knowledge concerning the disease to be treated, the physiological characteristics of the neonate, and the pharmacokinetics (PK) and pharmacodynamics (PD) of a given drug. It is critically important that all sources of information be leveraged to...