Anti-Interleukin-1 Beta/Tumor Necrosis Factor-Alpha IgY Antibodies Reduce Pathological Allergic Responses in Guinea Pigs with Allergic Rhinitis

• Main Authors: Hu Wei-xu (Author), Zhou Wen-yun (Author), Zhu Xi-ling (Author), Wen Zhu (Author), Wu Li-hua (Author), Wu Xiao-mu (Author), Wei Hui-ping (Author), Wang Wen-ding (Author), He Dan (Author), Xiang Qin (Author), Hu Guo-zhu (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aims to determine whether the combined blockade of IL-1β and TNF-α can alleviate the pathological allergic inflammatory reaction in the nasal mucosa and lung tissues in allergic rhinitis (AR) guinea pigs. Healthy guinea pigs treated with saline were used as the healthy controls. The AR gu...