Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.
A major impediment to eliminate lymphatic filariasis and onchocerciasis is the lack of effective short-course macrofilaricidal drugs or regimens that are proven to be safe for both infections. In this study we tested oxfendazole, an anthelmintic shown to be well tolerated in phase 1 clinical trials....
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2020-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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