MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

• Asıl Yazarlar: Stefanie Friedrich (Yazar), Remus Barbulescu (Yazar), Thomas Helleday (Yazar), Erik L. L. Sonnhammer (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2020-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogen...