MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

• मुख्य लेखकों: Stefanie Friedrich (लेखक), Remus Barbulescu (लेखक), Thomas Helleday (लेखक), Erik L. L. Sonnhammer (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2020-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogen...