Dexmedetomidine Protects Human Cardiomyocytes Against Ischemia-Reperfusion Injury Through α2-Adrenergic Receptor/AMPK-Dependent Autophagy

• Egile Nagusiak: Yingying Xiao (Egilea), Junpeng Li (Egilea), Lisheng Qiu (Egilea), Chuan Jiang (Egilea), Yanhui Huang (Egilea), Jinfen Liu (Egilea), Qi Sun (Egilea), Haifa Hong (Egilea), Lincai Ye (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background: Ischemia-reperfusion injury (I/R) strongly affects the prognosis of children with complicated congenital heart diseases (CHDs) who undergo long-term cardiac surgical processes. Recently, the α2-adrenergic receptor agonist Dexmedetomidine (Dex) has been reported to protect cardiomyocytes...