Dexmedetomidine Protects Human Cardiomyocytes Against Ischemia-Reperfusion Injury Through α2-Adrenergic Receptor/AMPK-Dependent Autophagy

• Main Authors: Yingying Xiao (Author), Junpeng Li (Author), Lisheng Qiu (Author), Chuan Jiang (Author), Yanhui Huang (Author), Jinfen Liu (Author), Qi Sun (Author), Haifa Hong (Author), Lincai Ye (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Fag: article
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Background: Ischemia-reperfusion injury (I/R) strongly affects the prognosis of children with complicated congenital heart diseases (CHDs) who undergo long-term cardiac surgical processes. Recently, the α2-adrenergic receptor agonist Dexmedetomidine (Dex) has been reported to protect cardiomyocytes...