The effect of the CCR5-delta32 deletion on global gene expression considering immune response and inflammation

• Main Authors: Hütter Gero (Author), Neumann Martin (Author), Nowak Daniel (Author), Klein Stefan (Author), Klüter Harald (Author), Hofmann Wolf-K (Author)
• Format: Book
• Published: BMC, 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The natural function of the C-C chemokine receptor type 5 (CCR5) is poorly understood. A 32 base pair deletion in the CCR5 gene (CCR5-delta32) located on chromosome 3 results in a non-functional protein. It is supposed that this dele...