The Effect of Hypertonic Saline on mRNA of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Polymorphonuclear Cells

• Main Authors: Sung-Hyuk Choi, MD, PhD (Author), Young-Hoon Yoon, MD, PhD (Author), Jung-Youn Kim, MD, PhD (Author), Sung-Woo Moon, MD, PhD (Author), Young-Duck Cho, MD, PhD (Author), Ji-Won Yeom (Author)
• Format: Book
• Published: Elsevier, 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hypertonic saline is often used to resuscitate patients experiencing shock. In such conditions, polymorphonuclear cells and Toll-like receptors (TLRs) form an essential part of early induced innate immunity. Objective: To investigate the immunomodulatory effect of hypertonic saline on po...