Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature.
Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed to IFN-γ which triggers their ability to kill the intracellular parasites. Consistent with this, transcriptional a...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2021-04-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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