Mining host candidate regulators of schistosomiasis-induced liver fibrosis in response to artesunate therapy through transcriptomics approach.

• Main Authors: Yajie Yuan (Author), Xinyue Lv (Author), Yahan Wu (Author), Youhong Weng (Author), Fangwei Dai (Author), Haojie Ding (Author), Riping Chen (Author), Bin Zheng (Author), Wenxia Zhao (Author), Qunbo Tong (Author), Jianzu Ding (Author), Di Lou (Author), Yunru Lai (Author), Xiaofeng Chu (Author), Longyou Zhao (Author), Shaohong Lu (Author), Qingming Kong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Artesunate (ART) has been reported to have an antifibrotic effect in various organs. The underlying mechanism has not been systematically elucidated. We aimed to clarify the effect of ART on liver fibrosis induced by Schistosoma japonicum (S. japonicum) in an experimen...