Vertical sleeve gastrectomy increases duodenal Lactobacillus spp. richness associated with the activation of intestinal HIF2α signaling and metabolic benefits

• Main Authors: Yikai Shao (Author), Simon S. Evers (Author), Jae Hoon Shin (Author), Sadeesh K. Ramakrishnan (Author), Nadejda Bozadjieva-Kramer (Author), Qiyuan Yao (Author), Yatrik M. Shah (Author), Darleen A. Sandoval (Author), Randy J. Seeley (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Vertical Sleeve Gastrectomy (VSG) is one of the most efficacious treatments for obesity and its comorbidities. Although a range of evidence suggests that alterations of the microbiota in the distal gut following VSG are pivotal to these metabolic improvements, the effect of surgery to alt...