Variation p.R1045H in MYH7 correlated with hypertrophic cardiomyopathy in a Chinese pedigree

• Main Authors: Yan Zhang (Author), Yiyi Shang (Author), Luo Liu (Author), Xiaoxue Ding (Author), Haiyan Wu (Author), Lijiang Li (Author), Mingjie Pang (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Inherited hypertrophic cardiomyopathy (HCM) is a common heart muscle disease that damages heart function and may cause the heart to suddenly stop beating. Genetic factors play an important role in HCM. Pedigree analysis is a good way to identify the genetic defects that cause dis...