A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA

• Κύριοι συγγραφείς: Zhengyang Zeng (Συγγραφέας), Shisong Han (Συγγραφέας), Wei Hong (Συγγραφέας), Yange Lang (Συγγραφέας), Fangfang Li (Συγγραφέας), Yongxiang Liu (Συγγραφέας), Zeyong Li (Συγγραφέας), Yingliang Wu (Συγγραφέας), Wenxin Li (Συγγραφέας), Xianzheng Zhang (Συγγραφέας), Zhijian Cao (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2016-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Hepatitis B virus (HBV) infection is a major cause of chronic active hepatitis, cirrhosis, and primary hepatocellular carcinoma, all of which are severe threats to human health. However, current clinical therapies for HBV are limited by potential side effects, toxicity, and drug-resistance. In this...