P2X7 in Cancer: From Molecular Mechanisms to Therapeutics

• मुख्य लेखकों: Romain Lara (लेखक), Elena Adinolfi (लेखक), Catherine A. Harwood (लेखक), Mike Philpott (लेखक), Julian A. Barden (लेखक), Francesco Di Virgilio (लेखक), Shaun McNulty (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

P2X7 is a transmembrane receptor expressed in multiple cell types including neurons, dendritic cells, macrophages, monocytes, B and T cells where it can drive a wide range of physiological responses from pain transduction to immune response. Upon activation by its main ligand, extracellular ATP, P2X...