Optimization of the Extragranular Excipient Composition of Paracetamol Tablet formulation using the Quality by Design Approach

• Main Authors: Yonni Eshovo Apeji (Author), Naima Avosuahi Ariko (Author), Olubunmi Jumoke Olayemi (Author), Adeniji Kehinde Olowosulu (Author), Avosuahi Rukayat Oyi (Author)
• Format: Book
• Published: Universidade de São Paulo, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The purpose of this study is to optimize the composition of extragranular excipients (EGE) and mixing time of granules with EGE of paracetamol tablet formulation using Design of Experiments (DoE) approach. The effect of the composition of EGE and the mixing time of granules with EGE on gran...