Discovery of novel IDH1-R132C inhibitors through structure-based virtual screening
Isocitrate dehydrogenase (IDH) belongs to a family of enzymes involved in glycometabolism. It is found in many living organisms and is one of the most mutated metabolic enzymes. In the current study, we identified novel IDH1-R132C inhibitors using docking-based virtual screening and cellular inhibit...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2022-09-01T00:00:00Z.
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