Transmission of chimeric HIV by mating in conventional mice: prevention by pre-exposure antiretroviral therapy and reduced susceptibility during estrus

• Main Authors: Eran Hadas (Author), Wei Chao (Author), Hongxia He (Author), Manisha Saini (Author), Eleen Daley (Author), Mohammed Saifuddin (Author), Galina Bentsman (Author), Eric Ganz (Author), David J. Volsky (Author), Mary Jane Potash (Author)
• Format: Book
• Published: The Company of Biologists, 2013-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Heterosexual transmission accounts for the majority of new human immunodeficiency virus (HIV) cases worldwide. The current approach to investigate HIV heterosexual transmission in animals involves application of virus stock to the vaginal surface, a method that does not reproduce the physiol...