Mutations Within the Transcription Factor PROP1 in a Cohort of Turkish Patients with Combined Pituitary Hormone Deficiency

• Principais autores: Fatma Derya Bulut (Autor), Semine Özdemir Dilek (Autor), Damla Kotan (Autor), Eda Mengen (Autor), Fatih Gürbüz (Autor), Bilgin Yüksel (Autor)
• Formato: Livro
• Publicado em: Galenos Yayincilik, 2020-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objective:Mutations of the genes encoding transcription factors which play important roles in pituitary morphogenesis, differentiation and maturation may lead to combined pituitary hormone deficiency (CPHD). PROP1 gene mutations are reported as the most frequent genetic aetiology of CHPD. The aim of...