Pharmacokinetics, Safety and Pharmacokinetics/Pharmacodynamics Analysis of Omadacycline in Chinese Healthy Subjects

• Главные авторы: Haijing Yang (Автор), Zhiwei Huang (Автор), Yuancheng Chen (Автор), Yusong Zhu (Автор), Guoying Cao (Автор), Jingjing Wang (Автор), Yan Guo (Автор), Jicheng Yu (Автор), Jufang Wu (Автор), Lichuan Liu (Автор), Jun Deng (Автор), Jing Liu (Автор), Harald Reinhart (Автор), Jing Zhang (Автор), Xiaojie Wu (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Objective: Omadacycline is a new type of aminomethylcycline antibiotic, having a broad antibacterial spectrum. But the pharmacokinetic characteristics and safety profile of the Chinese population remain unknown. It is also unclear whether the US-approved treatment regimen is applicable for the Chine...