Pharmacokinetics, Safety and Pharmacokinetics/Pharmacodynamics Analysis of Omadacycline in Chinese Healthy Subjects

• Main Authors: Haijing Yang (Author), Zhiwei Huang (Author), Yuancheng Chen (Author), Yusong Zhu (Author), Guoying Cao (Author), Jingjing Wang (Author), Yan Guo (Author), Jicheng Yu (Author), Jufang Wu (Author), Lichuan Liu (Author), Jun Deng (Author), Jing Liu (Author), Harald Reinhart (Author), Jing Zhang (Author), Xiaojie Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Omadacycline is a new type of aminomethylcycline antibiotic, having a broad antibacterial spectrum. But the pharmacokinetic characteristics and safety profile of the Chinese population remain unknown. It is also unclear whether the US-approved treatment regimen is applicable for the Chine...