Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-generation sequencing (mNGS)

• Prif Awduron: Yuanyi Yue (Awdur), Baohui Zhang (Awdur), Zhong He (Awdur), Yuling Zheng (Awdur), Xueqing Wang (Awdur), Qiang Zhang (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Objective: Inhaled corticosteroids (ICS) are widely used in chronic obstructive pulmonary disease (COPD) patients as a treatment option. However, ICS may also increase the risk of pneumonia and alter the composition of airway microbiota. In clinical application, the overuse of ICS exists pervasively...