Anticancer Effects of Phenoxazine Derivatives Revealed by Inhibition of Cell Growth and Viability, Disregulation of Cell Cycle, and Apoptosis Induction in HTLV-1-Positive Leukemia Cells

• Hoofdauteurs: Naoko Miyano-Kurosaki (Auteur), Kou Ikegami (Auteur), Kunihiko Kurosaki (Auteur), Takahiko Endo (Auteur), Hoshimi Aoyagi (Auteur), Mari Hanami (Auteur), Jun Yasumoto (Auteur), Akio Tomoda (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2009-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract.: Adult T-cell leukemia (ATL) is a malignant tumor of human CD4+ T cells infected with a human retrovirus, T lymphotropic virus type-1 (HTLV-1). The aim of the present study was to investigate the apoptotic effects of phenoxazines, 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one (Ph...