Auraptene Enhances Junction Assembly in Cerebrovascular Endothelial Cells by Promoting Resilience to Mitochondrial Stress through Activation of Antioxidant Enzymes and mtUPR

• Autori principali: Min Joung Lee (Autore), Yunseon Jang (Autore), Jiebo Zhu (Autore), Eunji Namgung (Autore), Dahyun Go (Autore), Changjun Seo (Autore), Xianshu Ju (Autore), Jianchen Cui (Autore), Yu Lim Lee (Autore), Hyoeun Kang (Autore), Hyeongseok Kim (Autore), Woosuk Chung (Autore), Jun Young Heo (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Junctional proteins in cerebrovascular endothelial cells are essential for maintaining the barrier function of the blood-brain barrier (BBB), thus protecting the brain from the infiltration of pathogens. The present study showed that the potential therapeutic natural compound auraptene (AUR) enhance...