NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos
SUMMARY Holoprosencephaly (HPE) is a common congenital defect that results from failed or incomplete forebrain cleavage. HPE is characterized by a wide clinical spectrum, with inter- and intrafamilial variability. This heterogeneity is not well understood and it has been suggested that HPE involves...
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| Main Authors: | , , , , , |
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| Format: | Book |
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The Company of Biologists,
2013-03-01T00:00:00Z.
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