Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation

• Hoofdauteurs: Chang-Ming Su (Auteur), Gui-Ge Hou (Auteur), Chun-Hua Wang (Auteur), Hong-Qin Zhang (Auteur), Cheng Yang (Auteur), Mei Liu (Auteur), Yun Hou (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Inhibition of NF-κB signalling has been demonstrated as a therapeutic option in treating inflammatory diseases and cancers. Herein, we synthesized novel dissymmetric 3,5-bis(arylidene)-4-piperidones (BAPs, 83-102) and characterized fully. MTT and ELISA assay were performed to screen the anti-hepatom...