Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation

• Main Authors: Chang-Ming Su (Author), Gui-Ge Hou (Author), Chun-Hua Wang (Author), Hong-Qin Zhang (Author), Cheng Yang (Author), Mei Liu (Author), Yun Hou (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inhibition of NF-κB signalling has been demonstrated as a therapeutic option in treating inflammatory diseases and cancers. Herein, we synthesized novel dissymmetric 3,5-bis(arylidene)-4-piperidones (BAPs, 83-102) and characterized fully. MTT and ELISA assay were performed to screen the anti-hepatom...